Preferential binding of K+ ions in the selectivity filter at equilibrium explains high selectivity of K+ channels
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چکیده
منابع مشابه
Preferential binding of K+ ions in the selectivity filter at equilibrium explains high selectivity of K+ channels
K(+) channels exhibit strong selectivity for K(+) ions over Na(+) ions based on electrophysiology experiments that measure ions competing for passage through the channel. During this conduction process, multiple ions interact within the region of the channel called the selectivity filter. Ion selectivity may arise from an equilibrium preference for K(+) ions within the selectivity filter or fro...
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ژورنال
عنوان ژورنال: Journal of General Physiology
سال: 2012
ISSN: 1540-7748,0022-1295
DOI: 10.1085/jgp.201210855